Glycerin

Glycerin

SCHEMBL6982256

C=CC(=O)OC(=O)C(=C)C.OCC(O)CO

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.36
ALDH1A1 P00352 8/20 0.34
LMNA P02545 1/20 0.32
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 1/20 0.32
THRB P10828 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TGFBR1 P36897 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Glycol SCHEMBL16752113 0.89 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8645258 0.89 TSHR (0.46) TSHRALDH1A1LMNATP53HIF1A
SCHEMBL27778816 0.84 ALDH1A1 (0.46) TSHRALDH1A1LMNATP53HIF1A
SCHEMBL65009 0.84 ALDH1A1 (0.46) TSHRALDH1A1LMNATP53HIF1A
Glycerin SCHEMBL7472223 0.82 TSHR (0.43) TSHRALDH1A1LMNATP53HIF1A
SCHEMBL20954076 0.82 ALDH1A1 (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6847941 0.82 ALDH1A1 (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL21616688 0.82 ALDH1A1 (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL20954079 0.82 ALDH1A1 (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9775693 0.82 ALDH1A1 (0.44) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0751161-B1 Sulfur-containing urethane-based resin composition, optical element and lens comprising this resin MITSUI CHEMICALS INC (JP) 2003-01-02 EP disclosed
US-5736609-A A POLYTHIO COMPOUND CONTAINING AT LEAST TWO MERCAPTO GROUPS, A POLYISO(THIO)CYANATE COMPOUND, AND A COMPOUND HAVING TWO OR MORE UNSATURATED REACTIVE GROUPS MITSUI TOATSU CHEMICALS, INC. (JP) 1998-04-07 US disclosed
EP-0751161-A2 Sulfur-containing urethane-based resin composition, optical element and lens comprising this resin MITSUI TOATSU CHEMICALS, Inc. (JP) 1997-01-02 EP disclosed