⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL936174 | 0.84 | — | — | |
| SCHEMBL4885755 | 0.82 | CRHBP (0.31) | — | |
| SCHEMBL182009 | 0.79 | — | — | |
| SCHEMBL5664529 | 0.79 | — | — | |
| SCHEMBL262994 | 0.78 | PYGM (0.35) | — | |
| SCHEMBL3622646 | 0.78 | — | — | |
| SCHEMBL16014041 | 0.77 | CRHBP (0.41) | — | |
| SCHEMBL7411108 | 0.76 | — | — | |
| SCHEMBL3328286 | 0.76 | — | — | |
| SCHEMBL15363888 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268422-A1 | INDOLES FOR TREATING DISEASES THAT CAN BE TREATED USING THYROID HORMONES | Bayer Aktiengesellschaft (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001070687-A1 | INDOLES FOR TREATING DISEASES THAT CAN BE TREATED USING THYROID HORMONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-27 | — | — | WO | disclosed |