Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.46 |
| ▸ | NPY1R | P25929 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21465270 | 0.82 | HTR2C (0.53) | ALDH1A1CYP2C9HTR2CHTR2BCYP19A1 | |
| SCHEMBL6760015 | 0.82 | SMN1; SMN2 (0.49) | ALDH1A1MAPK1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2821299 | 0.77 | TBXA2R (0.45) | — | |
| SCHEMBL2821696 | 0.77 | TBXA2R (0.39) | ALDH1A1NPY5RNPY1RDRD2ADRA2C | |
| SCHEMBL11216052 | 0.75 | GUSB (0.56) | ALDH1A1MAPK1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2865412 | 0.74 | NPY5R (0.72) | ALDH1A1NPY5RNPY1RDRD2ADRA2C | |
| SCHEMBL30737053 | 0.74 | KMT2A (0.59) | ALDH1A1MAPK1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4181150 | 0.74 | CYP19A1 (0.65) | ALDH1A1MAPK1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29791528 | 0.74 | CYP19A1 (0.65) | ALDH1A1MAPK1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30879299 | 0.73 | KMT2A (0.44) | ALDH1A1NPY5RNPY1RDRD2ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351928-A2 | NOVEL N(PHENYLSULPHONYL)GLYCINE DERIVATIVES AND THEIR THERAPEUTIC USE | LABORATOIRES FOURNIER S.A. (FR) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002053516-A2 | N(PHENYLSULPHONYL)GLYCINE DERIVATIVES AND THEIR THERAPEUTIC USE | LABORATOIRES FOURNIER SA (FR) | 2002-07-11 | — | — | WO | disclosed |