Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.57 |
| ▸ | GUSB | P08236 | 1/20 | 0.55 |
| ▸ | SLC12A2 | P55011 | 2/20 | 0.50 |
| ▸ | SLC12A5 | Q9H2X9 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29791528 | 1.00 | CYP19A1 (0.65) | CYP19A1CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL15657199 | 0.87 | LMNA (0.53) | CYP19A1CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL15660246 | 0.87 | ALDH1A1 (0.62) | CYP19A1CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL15677250 | 0.87 | LMNA (0.53) | CYP19A1CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL7207368 | 0.85 | POLB (0.55) | CYP19A1CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL4504076 | 0.84 | CYP19A1 (0.83) | CYP19A1ALDH1A1LMNAVCAM1SLC12A2 | |
| SCHEMBL15657633 | 0.84 | LMNA (0.53) | CYP19A1CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL15660010 | 0.84 | MAPT (0.54) | CYP19A1ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL3641949 | 0.81 | VCAM1 (0.55) | CYP19A1CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL11216052 | 0.80 | GUSB (0.56) | CYP19A1CYP1A2CYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348268-B | Substituted carbazole-indoles sulfonate derivatives and its preparation method and application | 四川大学 | 2018-11-16 | — | — | CN | disclosed |
| CN-105218538-B | Substitution coumarin-pyridine derivative, preparing method thereof and application thereof | 四川大学 | 2017-04-26 | — | — | CN | disclosed |
| CN-105348268-A | Substituted carbazole-indole sulfonate derivative, and preparation method therefor and use thereof | UNIV SICHUAN | 2016-02-24 | — | — | CN | disclosed |
| CN-105218538-A | Tonka bean camphor-pyridine derivate replaced and its production and use | UNIV SICHUAN | 2016-01-06 | — | — | CN | disclosed |
| US-9079870-B2 | Thiol mediated/activated prodrugs of sulfur dioxide (SO2) having anti-bacterial activity | INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH-PUNE (IN) | 2015-07-14 | — | — | US | disclosed |
| US-9079870-B2 | Thiol mediated/activated prodrugs of sulfur dioxide (SO2) having anti-bacterial activity | INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH-PUNE (IN) | 2015-07-14 | — | — | US | disclosed |
| US-9079870-B2 | Thiol mediated/activated prodrugs of sulfur dioxide (SO2) having anti-bacterial activity | INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH-PUNE (IN) | 2015-07-14 | — | — | US | disclosed |
| US-20140121211-A1 | THIOL MEDIATED/ACTIVATED PRODRUGS OF SULFUR DIOXIDE (SO2) HAVING ANTI-BACTERIAL ACTIVITY | INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH -PUNE (IN) | 2014-05-01 | — | — | US | disclosed |
| US-20140121211-A1 | THIOL MEDIATED/ACTIVATED PRODRUGS OF SULFUR DIOXIDE (SO2) HAVING ANTI-BACTERIAL ACTIVITY | INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH -PUNE (IN) | 2014-05-01 | — | — | US | disclosed |
| US-20140121211-A1 | THIOL MEDIATED/ACTIVATED PRODRUGS OF SULFUR DIOXIDE (SO2) HAVING ANTI-BACTERIAL ACTIVITY | INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH -PUNE (IN) | 2014-05-01 | — | — | US | disclosed |
| US-20090163697-A1 | Multicomponent coupling and glycopeptide synthesis with cyclic thioanhydrides | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140121211-A1 | THIOL MEDIATED/ACTIVATED PRODRUGS OF SULFUR DIOXIDE (SO2) HAVING ANTI-BACTERIAL ACTIVITY | TST, SQOR, MPST | CYP19A1 2620/4885CYP1A2 768/4885CYP3A4 239/4885 |
| US-20090163697-A1 | Multicomponent coupling and glycopeptide synthesis with cyclic thioanhydrides | LNPEP, CLSPN, GALNT14 | CYP19A1 4632/4885CYP1A2 4822/4885CYP3A4 4428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.