Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.45 |
| ▸ | NPY1R | P25929 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6418180 | 0.83 | MEN1 (0.49) | SMN1; SMN2LMNAHTTALDH1A1CYP1A2 | |
| SCHEMBL6418177 | 0.83 | MEN1 (0.49) | SMN1; SMN2LMNAHTTALDH1A1CYP1A2 | |
| SCHEMBL6982501 | 0.82 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5888030 | 0.79 | MEN1 (0.46) | SMN1; SMN2LMNAHTTALDH1A1CYP1A2 | |
| SCHEMBL5888033 | 0.79 | MEN1 (0.46) | SMN1; SMN2LMNAHTTALDH1A1CYP1A2 | |
| SCHEMBL19639684 | 0.74 | MEN1 (0.47) | SMN1; SMN2LMNAHTTALDH1A1CYP1A2 | |
| SCHEMBL4181150 | 0.73 | CYP19A1 (0.65) | LMNAALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29791528 | 0.73 | CYP19A1 (0.65) | LMNAALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27917787 | 0.72 | TGFBR1 (0.48) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL5724845 | 0.72 | TGFBR1 (0.61) | LMNAALDH1A1MGLLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063725-A1 | Novel n(phenylsulphonyl)glycine derivatives and their therapeutic use | LABORATORIES FOURNIER S.A. (FR) | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063725-A1 | Novel n(phenylsulphonyl)glycine derivatives and their therapeutic use | GLS, GLS2, GLRB | SMN1; SMN2 398/4885LMNA 3236/4885HTT 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.