Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 3/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31513766 | 1.00 | TSHR (0.47) | TSHRALOX15ATMUSP30RORC | |
| SCHEMBL351086 | 0.92 | TSHR (0.52) | TSHRALOX15ATMUSP30RORC | |
| SCHEMBL13771539 | 0.92 | TSHR (0.52) | TSHRALOX15ATMUSP30RORC | |
| SCHEMBL15595091 | 0.90 | TSHR (0.53) | TSHRALOX15ATMGPR119TACR1 | |
| SCHEMBL19462827 | 0.87 | RORC (0.50) | USP30RORCMEN1KMT2A | |
| SCHEMBL1430196 | 0.87 | RORC (0.50) | USP30RORCMEN1KMT2A | |
| SCHEMBL13572729 | 0.87 | MEN1 (0.41) | USP30RORCSCD5CYP11B2MEN1 | |
| SCHEMBL1309072 | 0.86 | RORC (0.51) | TSHRALOX15ATMRORCGPR119 | |
| SCHEMBL25269330 | 0.86 | GPR119 (0.48) | GPR119OPRD1OPRK1CYP11B2CYP3A4 | |
| SCHEMBL1430393 | 0.86 | USP30 (0.51) | TSHRALOX15ATMUSP30RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025087282-A1 | METHOD FOR PREPARING CHIRAL ALCOHOL COMPOUND | 中国科学院上海有机化学研究所 | 2025-05-01 | — | — | WO | claimed |
| CN-119899090-A | Preparation method of chiral alcohol compound | 中国科学院上海有机化学研究所 | 2025-04-29 | — | — | CN | claimed |
| WO-2025087282-A1 | METHOD FOR PREPARING CHIRAL ALCOHOL COMPOUND | 中国科学院上海有机化学研究所 | 2025-05-01 | — | — | WO | disclosed |
| CN-119899090-A | Preparation method of chiral alcohol compound | 中国科学院上海有机化学研究所 | 2025-04-29 | — | — | CN | disclosed |
| US-10428019-B2 | Chiral auxiliaries | WAVE LIFE SCIENCES LTD. (SG) | 2019-10-01 | — | — | US | disclosed |
| US-10428019-B2 | Chiral auxiliaries | WAVE LIFE SCIENCES LTD. (SG) | 2019-10-01 | — | — | US | disclosed |
| EP-2620428-B1 | ASYMMETRIC AUXILIARY GROUP | WAVE LIFE SCIENCES LTD (SG) | 2019-05-22 | — | — | EP | disclosed |
| EP-2620428-B1 | ASYMMETRIC AUXILIARY GROUP | WAVE LIFE SCIENCES LTD (SG) | 2019-05-22 | — | — | EP | disclosed |
| EP-2620428-A1 | ASYMMETRIC AUXILIARY GROUP | Chiralgen, Ltd. (JP) | 2013-07-31 | — | — | EP | disclosed |
| EP-2620428-A1 | ASYMMETRIC AUXILIARY GROUP | Chiralgen, Ltd. (JP) | 2013-07-31 | — | — | EP | disclosed |
| US-20130178612-A1 | CHIRAL AUXILIARIES | CHIRALGEN, LTD. (JP) | 2013-07-11 | — | — | US | disclosed |
| US-20130178612-A1 | CHIRAL AUXILIARIES | CHIRALGEN, LTD. (JP) | 2013-07-11 | — | — | US | disclosed |
| US-20130178612-A1 | CHIRAL AUXILIARIES | CHIRALGEN, LTD. (JP) | 2013-07-11 | — | — | US | disclosed |
| EP-0976745-B1 | 4-TETRAHYDROPYRIDYLPYRIMIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-6187781-B1 | CORTICOTROPIN RELEASING FACTOR RECEPTOR ANTAGONISTS; ALZHEIMER*S, HUNTINGTON, AND PARKINSON DISEASE; ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0976745-A1 | 4-TETRAHYDROPYRIDYLPYRIMIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2000-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130178612-A1 | CHIRAL AUXILIARIES | POLL, PCNA, POLM | TSHR 2617/4885ALOX15 4831/4885ATM 1632/4885 |
| US-10428019-B2 | Chiral auxiliaries | PCNA, POLL, TYMP | TSHR 2863/4885ALOX15 4721/4885ATM 2051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.