Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984269 | 0.96 | F10 (0.54) | F10F2PRSS1 | |
| SCHEMBL2707140 | 0.88 | F2 (0.59) | F10F2PRSS1CA1CA2 | |
| SCHEMBL13259958 | 0.88 | F2 (0.59) | F10F2PRSS1CA1CA2 | |
| SCHEMBL203869 | 0.88 | F2 (0.59) | F10F2PRSS1CA1CA2 | |
| SCHEMBL203868 | 0.88 | F2 (0.59) | F10F2PRSS1CA1CA2 | |
| SCHEMBL3724402 | 0.86 | F2 (0.56) | F10F2PRSS1 | |
| SCHEMBL5640985 | 0.86 | F2 (0.56) | F10F2PRSS1 | |
| SCHEMBL12525646 | 0.85 | MMP1 (0.55) | F10F2PRSS1 | |
| SCHEMBL12494289 | 0.85 | MMP1 (0.55) | F10F2PRSS1 | |
| SCHEMBL9608921 | 0.85 | F10 (0.60) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294716-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | Bristol-Myers Squibb Company (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096331-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |