Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.60 |
| ▸ | MMP1 | P03956 | 6/20 | 0.43 |
| ▸ | MMP3 | P08254 | 6/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4760677 | 0.91 | F2 (0.55) | F10F2PRSS1GAA | |
| SCHEMBL14277255 | 0.91 | F2 (0.55) | F10F2PRSS1GAA | |
| SCHEMBL3724402 | 0.89 | F2 (0.56) | F10F2PRSS1MMP1MMP3 | |
| SCHEMBL5640985 | 0.89 | F2 (0.56) | F10F2PRSS1MMP1MMP3 | |
| SCHEMBL9611950 | 0.89 | F2 (0.52) | F10F2PRSS1MMP1MMP3 | |
| SCHEMBL12525646 | 0.88 | MMP1 (0.55) | F10F2PRSS1MMP1MMP3 | |
| SCHEMBL12494289 | 0.88 | MMP1 (0.55) | F10F2PRSS1MMP1MMP3 | |
| SCHEMBL6984269 | 0.87 | F10 (0.54) | F10F2PRSS1MMP1MMP3 | |
| SCHEMBL21165916 | 0.86 | F2 (0.53) | F10F2PRSS1MMP1MMP3 | |
| SCHEMBL6982747 | 0.85 | F10 (0.57) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457896-A1 | Tripeptides as caspase modulators | Idun Pharmaceuticals, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |
| EP-2457895-A1 | Tetrapeptide analogs | Idun Pharmaceuticals, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |