Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268589 | 0.85 | HIF1A (0.50) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL803931 | 0.82 | SMN1; SMN2 (0.52) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL6594704 | 0.79 | NPC1 (0.47) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL16447717 | 0.79 | SLC6A2 (0.52) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL21114340 | 0.79 | SMN1; SMN2 (0.47) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL6977671 | 0.78 | CYP3A4 (0.49) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL28972746 | 0.77 | HIF1A (0.46) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL30853559 | 0.76 | TRPA1 (0.49) | TRPA1SMN1; SMN2HIF1ASLC6A2TAAR1 | |
| SCHEMBL6975887 | 0.76 | MMP8 (0.39) | TRPA1PPARGPPARACYP3A4ALDH1A1 | |
| SCHEMBL6975879 | 0.76 | MMP8 (0.39) | TRPA1PPARGPPARACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4840875-A | Desensitizing gum for lithographic printing plate comprising a polybasic and monoester of polysaccharide | FUJI PHOTO FILM CO., LTD. (JP) | 1989-06-20 | — | — | US | claimed |
| US-4698411-A | Polyester resins | PHILLIPS PETROLEUM COMPANY (US) | 1987-10-06 | — | — | US | claimed |
| US-RE38132-E1 | Phenylpyrrolidines, phenylimidazolidines,3-phenyl-1,3-oxizolidines and 3-phenyl-1,3-thiazolidines and their use in the treatment of inflammatory disease | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-06-03 | — | — | US | disclosed |
| EP-0966447-B1 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMA (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6355664-B1 | ADULT RESPIRATORY DISTRESS SYNDROME AND CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-03-12 | — | — | US | disclosed |
| CN-1249748-A | Small molecules useful in treatment of inflamatory disease | BOEHRINGER INGELHELM PHARMACEU (US) | 2000-04-05 | — | — | CN | disclosed |
| EP-0966447-A1 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998039303-A1 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1998-09-11 | — | — | WO | disclosed |
| US-4840875-A | Desensitizing gum for lithographic printing plate comprising a polybasic and monoester of polysaccharide | FUJI PHOTO FILM CO., LTD. (JP) | 1989-06-20 | — | — | US | disclosed |
| US-4698411-A | Polyester resins | PHILLIPS PETROLEUM COMPANY (US) | 1987-10-06 | — | — | US | disclosed |