Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 14/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982844 | 1.00 | CCR5 (0.58) | CCR5OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6974429 | 0.92 | OPRK1 (0.54) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6974434 | 0.92 | OPRK1 (0.54) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL9450018 | 0.89 | OPRK1 (0.65) | CCR5OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6979166 | 0.89 | OPRK1 (0.58) | CCR5OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6979168 | 0.89 | OPRK1 (0.58) | CCR5OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL27567265 | 0.89 | OPRK1 (0.58) | CCR5OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6981228 | 0.88 | OPRK1 (0.61) | CCR5OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6979508 | 0.88 | OPRK1 (0.61) | CCR5OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6973674 | 0.88 | OPRK1 (0.61) | CCR5OPRK1CYP2D6OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817772-B1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER (US) | 2003-01-29 | — | — | EP | disclosed |
| WO-1996030339-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1996-10-03 | — | — | WO | disclosed |