Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977143 | 0.86 | MAPT (0.41) | MAPTHTTABCC9ABCC8KCNJ11 | |
| SCHEMBL6981268 | 0.84 | RAF1 (0.43) | MAPTHTTRAF1RAB9AMEN1 | |
| SCHEMBL11575689 | 0.72 | CYP1A2 (0.39) | PPARAPDK1PDK2PDK3PDK4 | |
| SCHEMBL6975862 | 0.71 | RAF1 (0.42) | RAF1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL12782339 | 0.69 | RAB9A (0.60) | MAPTHTTRAB9AMEN1KMT2A | |
| SCHEMBL11749750 | 0.67 | RAB9A (0.60) | RAF1RAB9AMEN1KMT2AGAA | |
| SCHEMBL11751476 | 0.66 | KMT2A (0.50) | MAPTHTTRAB9AMEN1KMT2A | |
| SCHEMBL11255956 | 0.65 | MEN1 (0.42) | MAPTHTTRAB9AMEN1KMT2A | |
| SCHEMBL6984071 | 0.65 | PPARG (0.45) | MAPTHTTRAF1MEN1KMT2A | |
| SCHEMBL25494271 | 0.65 | MEN1 (0.45) | MAPTHTTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030835-B1 | UREA DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | ASTRAZENECA UK LTD (GB) | 2003-01-22 | — | — | EP | disclosed |
| US-6344570-B1 | ANTISTICKING AGENTS FOR CELLS | ASTRAZENECA UK LIMITED (GB) | 2002-02-05 | — | — | US | disclosed |