Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834057 | 0.84 | KMT2A (0.66) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL279656 | 0.77 | ALDH1A1 (0.59) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL7877536 | 0.77 | KMT2A (0.66) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL5974770 | 0.77 | KMT2A (0.73) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL28673562 | 0.77 | KMT2A (0.71) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL16433566 | 0.76 | KMT2A (0.57) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL30478066 | 0.76 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL474709 | 0.76 | KMT2A (0.70) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL5340030 | 0.76 | MEN1 (0.89) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14641620 | 0.76 | KMT2A (0.65) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296978-A2 | N-UREIDOHETEROCYCLOAKLYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002002525-A2 | N-UREIDOHETEROCYCLOAKLYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-01-10 | — | — | WO | disclosed |