Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5974770 | 0.85 | KMT2A (0.73) | KMT2AMEN1TDP1ALDH1A1NPC1 | |
| SCHEMBL7877536 | 0.85 | KMT2A (0.66) | KMT2AMEN1TDP1ALDH1A1NPC1 | |
| SCHEMBL5340030 | 0.84 | MEN1 (0.89) | KMT2AMEN1TDP1ALDH1A1NPC1 | |
| SCHEMBL474709 | 0.84 | KMT2A (0.70) | KMT2AMEN1TDP1ALDH1A1NPC1 | |
| SCHEMBL6983111 | 0.84 | KMT2A (0.56) | KMT2AMEN1TDP1ALDH1A1NPC1 | |
| SCHEMBL4102809 | 0.82 | KMT2A (0.73) | KMT2AMEN1TDP1ALDH1A1NPC1 | |
| SCHEMBL6930688 | 0.81 | KMT2A (0.62) | KMT2AMEN1TDP1ALDH1A1NPC1 | |
| SCHEMBL279656 | 0.81 | ALDH1A1 (0.59) | KMT2AMEN1TDP1ALDH1A1NPC1 | |
| SCHEMBL13210704 | 0.81 | KMT2A (0.81) | KMT2AMEN1TDP1ALDH1A1NPC1 | |
| SCHEMBL5456725 | 0.81 | ALDH1A1 (0.83) | KMT2AMEN1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | KMT2A 2853/4885MEN1 4132/4885TDP1 2738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.