Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 2/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.36 |
| ▸ | PTPN12 | Q05209 | 2/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL649652 | 0.92 | RNASEL (0.40) | ABL1HPGDRNASELTUBB4ATUBB | |
| SCHEMBL652415 | 0.92 | MAPT (0.41) | PTPN7DUSP3PTPN12PTPN22ABL1 | |
| SCHEMBL703259 | 0.91 | MEN1 (0.38) | PTPN7PTPN12PTPN22MAPTHPGD | |
| SCHEMBL653897 | 0.88 | MAPT (0.40) | PTPN7DUSP3PTPN12PTPN22ABL1 | |
| SCHEMBL653900 | 0.88 | MAPT (0.45) | PTPN7DUSP3PTPN12PTPN22MAPT | |
| SCHEMBL651683 | 0.85 | MAPT (0.40) | PTPN7DUSP3PTPN12PTPN22ABL1 | |
| SCHEMBL653370 | 0.85 | MAPT (0.40) | PTPN7DUSP3PTPN12PTPN22ABL1 | |
| SCHEMBL652215 | 0.84 | HPGD (0.36) | PTPN7DUSP3PTPN12PTPN22ABL1 | |
| SCHEMBL650980 | 0.84 | MAPT (0.42) | PTPN7DUSP3PTPN12PTPN22MAPT | |
| SCHEMBL650979 | 0.84 | MAPT (0.42) | PTPN7DUSP3PTPN12PTPN22MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-8119812-B2 | Thiazolidinone derivative | SBI BIOTECH CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | CDC7, CDK17, CDCA2 | PTPN7 437/4885DUSP3 579/4885PTPN12 1722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.