Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.45 |
| ▸ | TSPO | P30536 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694888 | 1.00 | HTR6 (0.51) | HTR6PLA2G2ATSPO | |
| SCHEMBL6976610 | 0.91 | HTR6 (0.48) | HTR6PLA2G2ATSPO | |
| SCHEMBL6976613 | 0.89 | HTR6 (0.46) | HTR6PLA2G2ATSPO | |
| SCHEMBL6983058 | 0.89 | HTR6 (0.46) | HTR6PLA2G2ATSPO | |
| SCHEMBL6982832 | 0.89 | HTR6 (0.46) | HTR6PLA2G2ATSPO | |
| SCHEMBL6982837 | 0.89 | HTR6 (0.46) | HTR6PLA2G2ATSPO | |
| SCHEMBL6697710 | 0.88 | HTR6 (0.47) | HTR6PLA2G2ATSPO | |
| SCHEMBL29862369 | 0.88 | PLA2G2A (0.51) | HTR6PLA2G2A | |
| SCHEMBL30007568 | 0.88 | HTR6 (0.43) | HTR6PLA2G2ATSPO | |
| SCHEMBL818729 | 0.88 | PLA2G2A (0.51) | HTR6PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839806-B1 | Substituted tricyclics | LILLY CO ELI (US) | 2003-07-09 | — | — | EP | disclosed |
| WO-1998018464-A1 | SUBSTITUTED TRICYCLICS | ELI LILLY AND COMPANY (US) | 1998-05-07 | — | — | WO | disclosed |
| EP-0839806-A1 | Substituted tricyclics | ELI LILLY AND COMPANY (US) | 1998-05-06 | — | — | EP | disclosed |