Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984361 | 0.89 | PTGER4 (0.39) | PTGER4NPC1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL6981028 | 0.88 | NPC1 (0.48) | PTGER4NPC1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL6979414 | 0.86 | LTB4R2 (0.40) | PTGER4NPC1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL6980417 | 0.86 | PTGER4 (0.39) | PTGER4NPC1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL6985248 | 0.83 | MAPT (0.42) | PTGER4NPC1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL6986544 | 0.81 | PTGER4 (0.39) | PTGER4NPC1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL6977399 | 0.79 | PTGER4 (0.42) | PTGER4NPC1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7409214 | 0.79 | PTGER4 (0.38) | PTGER4NPC1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL6977743 | 0.78 | PTGER4 (0.46) | PTGER4MAPTMEN1KMT2AFPR1 | |
| SCHEMBL6985399 | 0.78 | NOTUM (0.36) | PTGER4NPC1MAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |