Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.37 |
| ▸ | OXTR | P30559 | 2/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984361 | 0.92 | PTGER4 (0.39) | LTB4R2AVPR2OXTRAVPR1APTGER4 | |
| SCHEMBL6981028 | 0.88 | NPC1 (0.48) | LTB4R2PTGER4MAPTSMN1; SMN2MEN1 | |
| SCHEMBL6980417 | 0.86 | PTGER4 (0.39) | PTGER4MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL6983537 | 0.86 | PTGER4 (0.38) | LTB4R2PTGER4MAPTSMN1; SMN2LMNA | |
| SCHEMBL7960198 | 0.84 | MEN1 (0.43) | LTB4R2AVPR2OXTRAVPR1AMAPT | |
| SCHEMBL6986544 | 0.84 | PTGER4 (0.39) | AVPR2OXTRAVPR1APTGER4MAPT | |
| SCHEMBL6977399 | 0.80 | PTGER4 (0.42) | PTGER4MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL7409214 | 0.79 | PTGER4 (0.38) | AVPR2PTGER4MAPTSMN1; SMN2GAA | |
| SCHEMBL6981595 | 0.79 | LTB4R2 (0.46) | LTB4R2AVPR2OXTRAVPR1AMAPT | |
| SCHEMBL6979177 | 0.78 | CCR5 (0.39) | PTGER4MAPTSMN1; SMN2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |