Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984365 | 0.84 | PLA2G2A (0.55) | PLA2G2A | |
| SCHEMBL7517440 | 0.82 | TSHR (0.56) | PLA2G2APLA2G1B | |
| SCHEMBL6920467 | 0.82 | PLA2G2A (0.55) | PLA2G2APLA2G1B | |
| SCHEMBL6781791 | 0.82 | P2RX4 (0.43) | PLA2G2A | |
| SCHEMBL6771322 | 0.82 | EGFR (0.50) | PLA2G2A | |
| SCHEMBL6695139 | 0.81 | PLA2G2A (0.51) | PLA2G2A | |
| SCHEMBL6688548 | 0.81 | PLA2G2A (0.46) | PLA2G2A | |
| SCHEMBL6129647 | 0.81 | PLA2G2A (0.50) | PLA2G2APLA2G1B | |
| SCHEMBL8574427 | 0.80 | PLA2G2A (0.46) | PLA2G2A | |
| SCHEMBL27507588 | 0.78 | PARP1 (0.47) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839806-B1 | Substituted tricyclics | LILLY CO ELI (US) | 2003-07-09 | — | — | EP | disclosed |
| WO-1998018464-A1 | SUBSTITUTED TRICYCLICS | ELI LILLY AND COMPANY (US) | 1998-05-07 | — | — | WO | disclosed |
| EP-0839806-A1 | Substituted tricyclics | ELI LILLY AND COMPANY (US) | 1998-05-06 | — | — | EP | disclosed |