Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 8/20 | 0.73 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.73 |
| ▸ | MMP3 | P08254 | 3/20 | 0.73 |
| ▸ | MMP13 | P45452 | 3/20 | 0.73 |
| ▸ | GFER | P55789 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.59 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222369 | 0.85 | ADAMTS5 (0.74) | AKR1B1PTPN1ADAMTS5 | |
| SCHEMBL6887210 | 0.85 | AKR1B1 (1.00) | AKR1B1PTPN1MMP3MMP13GFER | |
| SCHEMBL19736049 | 0.85 | AKR1B1 (1.00) | AKR1B1PTPN1MMP3MMP13GFER | |
| SCHEMBL6887214 | 0.85 | AKR1B1 (1.00) | AKR1B1PTPN1MMP3MMP13GFER | |
| SCHEMBL19736228 | 0.81 | AKR1B1 (1.00) | AKR1B1PTPN1MMP3MMP13GFER | |
| SCHEMBL17319262 | 0.81 | AKR1B1 (1.00) | AKR1B1PTPN1MMP3MMP13GFER | |
| SCHEMBL1060503 | 0.81 | AKR1B1 (1.00) | AKR1B1PTPN1MMP3MMP13GFER | |
| SCHEMBL19736085 | 0.78 | MEN1 (1.00) | AKR1B1PTPN1MMP3MMP13GFER | |
| SCHEMBL29408626 | 0.78 | MEN1 (1.00) | AKR1B1PTPN1MMP3MMP13GFER | |
| SCHEMBL25992272 | 0.78 | AKR1B1 (0.85) | AKR1B1PTPN1MMP3MMP13GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313471-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | Oxford GlycoSciences (UK) Limited (GB) | 2003-05-28 | — | — | EP | claimed |
| WO-2002017915-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 2002-03-07 | — | — | WO | claimed |