Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15480812 | 0.86 | ALDH1A1 (0.52) | ALDH1A1POLBNPSR1GLSRAB9A | |
| SCHEMBL13398310 | 0.78 | SMN1; SMN2 (0.40) | ALDH1A1POLBNPSR1GLSRAB9A | |
| SCHEMBL15042202 | 0.75 | ALDH1A1 (0.47) | ALDH1A1POLBNPSR1GLSRAB9A | |
| SCHEMBL28656883 | 0.74 | ALDH1A1 (0.39) | ALDH1A1POLBGLS | |
| Hydrochloric Acid SCHEMBL3710488 | 0.71 | CA1 (0.40) | ALDH1A1POLBGLSRAB9AATM | |
| SCHEMBL24259127 | 0.71 | ALDH1A1 (0.45) | ALDH1A1POLBNPSR1GLSRAB9A | |
| SCHEMBL14773409 | 0.71 | ALDH1A1 (0.49) | ALDH1A1POLBGLSRAB9AATM | |
| SCHEMBL22368217 | 0.70 | ALDH1A1 (0.73) | ALDH1A1POLBNPSR1GLSRAB9A | |
| SCHEMBL6553986 | 0.70 | ALDH1A1 (0.73) | ALDH1A1POLBNPSR1GLSRAB9A | |
| SCHEMBL31244838 | 0.70 | ALDH1A1 (0.73) | ALDH1A1POLBNPSR1GLSRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759755-B1 | Thiadiazolylalkoxyphenyl derivatives, their preparation and their use anti-picornaviral agents | SANOFI SYNTHELABO (FR) | 2003-08-13 | — | — | EP | disclosed |
| CN-1095664-C | Thiadiazoles and their use as antipicornaviral agent | SANNOFFE SYNTHELAB S A (FR) | 2002-12-11 | — | — | CN | disclosed |
| US-5821257-A | Thiadiazoles and their uses as antipicornaviral agents | SANOFI (FR) | 1998-10-13 | — | — | US | disclosed |
| US-5750527-A | VIRICIDES | SANOFI (FR) | 1998-05-12 | — | — | US | disclosed |
| US-5650419-A | Thiadiazoles and their use as antipicornaviral agents | SANOFI, S.A. | 1997-07-22 | — | — | US | disclosed |
| CN-1148339-A | Thiadiazoles and their use as antipicornaviral agent | SANOFI WINTHROP INC (US) | 1997-04-23 | — | — | CN | disclosed |
| US-5567719-A | Thiadiazoles and their use as antipicornaviral agents | STERLING WINTHROP, INC. (US) | 1996-10-22 | — | — | US | disclosed |
| US-5453433-A | Viricides; antiseptics to decontaminate polio, rhino and coxsackie viruses | STERLING WINTHROP INC. (US) | 1995-09-26 | — | — | US | disclosed |