Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 5/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983654 | 0.82 | STIM1 (0.37) | ABL1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6983656 | 0.76 | USP30 (0.35) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL6988320 | 0.75 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL83319 | 0.73 | NPC1 (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL6967654 | 0.73 | TAAR1 (0.44) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL6985888 | 0.73 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL6987711 | 0.73 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL6981649 | 0.72 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL6986680 | 0.71 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8164187 | 0.71 | MAPT (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670307-B2 | Such as 2-(2,6-difluorophenyl)-4-(4-(2-ethoxypyridin-5-yl) phenyl)oxazoline; for administration to livestock | HOECHST SCHERING AGREVO GMBH (DE) | 2003-12-30 | — | — | US | disclosed |
| EP-1087967-B1 | 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2003-10-22 | — | — | EP | disclosed |
| US-20020068828-A1 | 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides | BAYER CROPSCIENCE AG (DE) | 2002-06-06 | — | — | US | disclosed |
| US-6265350-B1 | CONTROLLING HARMFUL FUNGI, INSECTS, ACARINA, MOLLUSKS AND NEMATODES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-07-24 | — | — | US | disclosed |
| EP-1087967-A1 | 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES | Aventis CropScience GmbH (DE) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065901-A1 | 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 1999-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068828-A1 | 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides | MT-CO1, OXA1L, MT-CO3 | ABL1 3353/4885ALDH1A1 127/4885SMN1; SMN2 1719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.