Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298171 | 1.00 | AOC3 (0.61) | AOC3GAAALDH1A1MAPTTAAR1 | |
| Hydrochloric Acid SCHEMBL6983699 | 0.98 | AOC3 (0.59) | AOC3GAAALDH1A1MAPTTAAR1 | |
| SCHEMBL336019 | 0.84 | AOC3 (0.65) | AOC3GAAALDH1A1MAPTTAAR1 | |
| SCHEMBL9054504 | 0.84 | AOC3 (0.65) | AOC3GAAALDH1A1MAPTTAAR1 | |
| SCHEMBL7152554 | 0.84 | AOC3 (0.65) | AOC3GAAALDH1A1MAPTTAAR1 | |
| SCHEMBL4450372 | 0.82 | GAA (0.58) | AOC3GAAALDH1A1MAPTMEN1 | |
| SCHEMBL9245675 | 0.82 | GAA (0.58) | AOC3GAAALDH1A1MAPTMEN1 | |
| SCHEMBL5488204 | 0.82 | AOC3 (0.58) | AOC3GAAALDH1A1MAPTHTR1A | |
| SCHEMBL19407135 | 0.81 | GAA (0.61) | AOC3GAAALDH1A1MAPTMEN1 | |
| SCHEMBL14354458 | 0.81 | GAA (0.61) | AOC3GAAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286975-A1 | BICLYCLIC CYCLOHEXYLAMINES AND THEIR USE AS NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001092239-A1 | BICICLIC CYCLOHEXYLAMINES AND THEIR USE AS NMDA RECEPTOR ANTOGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-12-06 | — | — | WO | disclosed |