Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3729724 | 0.79 | SRC (0.50) | SRCSLC13A5HPGD | |
| SCHEMBL6986247 | 0.78 | POLB (0.48) | SRCSLC13A5 | |
| SCHEMBL988070 | 0.78 | TSHR (0.50) | SRCADRA1AADRA1DADRA1BTSHR | |
| SCHEMBL30647012 | 0.77 | SRC (0.51) | SRCSLC13A5HPGD | |
| SCHEMBL1520555 | 0.77 | SRC (0.51) | SRCSLC13A5HPGD | |
| SCHEMBL5535285 | 0.76 | SRC (0.50) | SRCSLC13A5MAPK1 | |
| SCHEMBL745468 | 0.76 | F2 (0.38) | SLC13A5TP53TDP1 | |
| SCHEMBL9410317 | 0.75 | SRC (0.47) | SRCTRPA1SLC13A5MAPK1 | |
| SCHEMBL3630293 | 0.75 | SRC (0.50) | SRCADRA1AADRA1DADRA1BTRPA1 | |
| SCHEMBL749589 | 0.75 | MAPT (0.48) | SRCSLC13A5TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |