Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983702 | 0.78 | SRC (0.47) | SRCSLC13A5 | |
| SCHEMBL1520555 | 0.78 | SRC (0.51) | SRCKDM4EKMT2ASLC13A5 | |
| SCHEMBL30647012 | 0.78 | SRC (0.51) | SRCKDM4EKMT2ASLC13A5 | |
| SCHEMBL3729724 | 0.77 | SRC (0.50) | SRCKDM4ESLC13A5 | |
| SCHEMBL5535285 | 0.74 | SRC (0.50) | SRCKDM4ESLC13A5 | |
| SCHEMBL749668 | 0.74 | SRC (0.47) | SRCKDM4EKMT2ASLC13A5L3MBTL1 | |
| SCHEMBL3630293 | 0.73 | SRC (0.50) | POLBSRCKDM4EKMT2AHTT | |
| SCHEMBL6986243 | 0.73 | KDM4E (0.62) | POLBKDM4EKMT2AMAOBEGFR | |
| SCHEMBL9001638 | 0.73 | POLB (0.75) | POLBKDM4EKMT2AMAOBEGFR | |
| SCHEMBL9120591 | 0.71 | L3MBTL1 (0.45) | SRCKMT2AHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |