Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072322 | 0.88 | ITGB3 (0.44) | ITGB3ITGA2BSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7385984 | 0.84 | ITGB3 (0.48) | ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL7353558 | 0.84 | ITGB3 (0.65) | ITGB3ITGA2BPOLBKMT2AMEN1 | |
| SCHEMBL6983683 | 0.81 | ITGB3 (0.71) | ITGB3ITGA2B | |
| SCHEMBL7346039 | 0.80 | ITGB3 (0.50) | ITGB3ITGA2BPOLBKMT2AHTT | |
| SCHEMBL6985451 | 0.80 | ITGB3 (0.47) | ITGB3ITGA2BPOLBKMT2AMEN1 | |
| SCHEMBL7345488 | 0.80 | ITGB3 (0.54) | ITGB3ITGA2BPOLBKMT2AMEN1 | |
| SCHEMBL7348197 | 0.78 | ITGB3 (0.63) | ITGB3ITGA2BPOLBMAPT | |
| SCHEMBL8906494 | 0.78 | CA1 (0.46) | ITGB3ITGA2BPOLB | |
| SCHEMBL8906500 | 0.78 | CA1 (0.46) | ITGB3ITGA2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630366-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-0539343-B1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO CO (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |