Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983705 | 0.88 | ITGB3 (0.47) | ITGB3ITGA2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7353182 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6981913 | 0.84 | ITGB3 (0.63) | ITGB3ITGA2BGAA | |
| SCHEMBL7348958 | 0.82 | ITGB3 (0.51) | ITGB3ITGA2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7346612 | 0.81 | ITGB3 (0.50) | ITGB3ITGA2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7351423 | 0.80 | ITGB3 (0.56) | ITGB3ITGA2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6981928 | 0.80 | RAB9A (0.45) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL7349536 | 0.79 | ITGB3 (0.48) | ITGB3ITGA2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7346544 | 0.79 | ITGB3 (0.50) | ITGB3ITGA2BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7534287 | 0.78 | ITGB3 (0.70) | ITGB3ITGA2BSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539343-B1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO CO (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0630366-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. Searle & Co. (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| WO-1993008164-A1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |