Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 6/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5553589 | 0.85 | ACHE (0.49) | BIRC2TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL5199197 | 0.84 | ACHE (0.44) | TAS1R3TAS1R1CA1CA2EPHX1 | |
| SCHEMBL5199193 | 0.84 | ACHE (0.44) | TAS1R3TAS1R1CA1CA2EPHX1 | |
| SCHEMBL6976697 | 0.84 | MAPT (0.41) | BIRC2TAS1R3TAS1R1HRH3NPC1 | |
| SCHEMBL11783967 | 0.84 | ERAP2 (0.46) | BIRC2TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL10766995 | 0.84 | ERAP2 (0.46) | BIRC2TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL8823889 | 0.84 | ERAP2 (0.46) | BIRC2TAS1R3TAS1R1CA1CA2 | |
| SCHEMBL5198185 | 0.83 | ZDHHC7 (0.42) | BIRC2TAS1R3TAS1R1NPC1HPGD | |
| SCHEMBL4778608 | 0.83 | CA1 (0.41) | BIRC2TAS1R3TAS1R1HRH3CA1 | |
| SCHEMBL12296373 | 0.83 | HDAC2 (0.48) | BIRC2TAS1R3TAS1R1L3MBTL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282594-A1 | BRANCHED AMINO ACIDS | Medivir UK Ltd (GB) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001087821-A1 | BRANCHED AMINO ACIDS | MEDIVIR UK LIMITED (GB) | 2001-11-22 | — | — | WO | disclosed |