Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PNKP | Q96T60 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987548 | 0.84 | ELANE (0.47) | ELANECYP2C19 | |
| Water SCHEMBL7515031 | 0.82 | ELANE (0.45) | ELANECYP2C19 | |
| SCHEMBL6987940 | 0.79 | ELANE (0.48) | ELANECYP2C19 | |
| SCHEMBL6992279 | 0.78 | ELANE (0.42) | ELANECYP2C19 | |
| SCHEMBL4837251 | 0.77 | NR1H4 (0.41) | ELANE | |
| SCHEMBL5387987 | 0.76 | NR1H4 (0.38) | CYP2C19 | |
| SCHEMBL3837697 | 0.76 | NR1H4 (0.42) | ELANE | |
| SCHEMBL4659695 | 0.75 | NR1H4 (0.41) | ELANE | |
| SCHEMBL5224055 | 0.75 | NR1H4 (0.39) | — | |
| SCHEMBL4598886 | 0.74 | NR1H4 (0.43) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345918-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050051-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-06-27 | — | — | WO | disclosed |