Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | CCKAR | P32238 | 1/20 | 0.30 |
| ▸ | CCKBR | P32239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507444 | 0.88 | ELANE (0.45) | ELANECYP2C19KDM4EPKMALDH1A1 | |
| SCHEMBL6987940 | 0.88 | ELANE (0.48) | ELANECYP2C19KDM4EPKMALDH1A1 | |
| Water SCHEMBL7515031 | 0.82 | ELANE (0.45) | ELANECYP2C19KDM4EPKMALDH1A1 | |
| SCHEMBL6983814 | 0.78 | ELANE (0.37) | ELANECYP2C19 | |
| SCHEMBL6993400 | 0.78 | ELANE (0.42) | ELANECYP2C19KDM4EPKMALDH1A1 | |
| SCHEMBL6993131 | 0.76 | ELANE (0.41) | ELANECYP2C19KDM4EPKMALDH1A1 | |
| SCHEMBL7512573 | 0.75 | ELANE (0.44) | ELANECYP2C19KDM4EPKMALDH1A1 | |
| Ethyl Bromo Acetate SCHEMBL7509727 | 0.74 | ALDH1A1 (0.39) | ELANECYP2C19KDM4EPKMALDH1A1 | |
| SCHEMBL6993818 | 0.74 | ELANE (0.43) | ELANECYP2C19KDM4EPKMALDH1A1 | |
| SCHEMBL4598886 | 0.73 | NR1H4 (0.43) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345918-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050051-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-06-27 | — | — | WO | disclosed |