Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950431 | 0.76 | L3MBTL1 (0.44) | TRPV1ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL6987576 | 0.74 | TSHR (0.43) | ALDH1A1TSHRLMNAL3MBTL1MEN1 | |
| SCHEMBL6703841 | 0.72 | ZDHHC7 (0.46) | TRPV1ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL11168309 | 0.67 | ALOX15 (0.50) | TSHRLMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL5318813 | 0.67 | ALOX15 (0.50) | TSHRLMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL7335421 | 0.67 | ALOX15 (0.50) | TSHRLMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL6060692 | 0.66 | TRPV1 (0.64) | TRPV1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL24765233 | 0.66 | TAAR1 (0.56) | HTR2ATAAR1 | |
| SCHEMBL2560789 | 0.65 | HTR2A (0.73) | HTR2ATSHRLMNACYP1A2CYP3A4 | |
| SCHEMBL10394093 | 0.64 | TAAR1 (0.61) | HTR2AALDH1A1TSHRLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |