Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 2/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6985728 | 0.84 | FAAH (0.39) | ALDH1A1CNR1CNR2FAAHACHE | |
| SCHEMBL6982744 | 0.82 | EP300 (0.45) | EP300HTR4ALDH1A1SMN1; SMN2KDM1A | |
| SCHEMBL6990414 | 0.80 | HTR4 (0.43) | EP300HTR4ALDH1A1SMN1; SMN2KDM1A | |
| SCHEMBL6985733 | 0.80 | HTR4 (0.43) | EP300HTR4ALDH1A1SMN1; SMN2KDM1A | |
| SCHEMBL6989025 | 0.80 | HTR4 (0.43) | EP300HTR4ALDH1A1SMN1; SMN2KDM1A | |
| SCHEMBL6985413 | 0.79 | HTR4 (0.43) | EP300HTR4ALDH1A1SMN1; SMN2KDM1A | |
| SCHEMBL6986612 | 0.79 | HTR4 (0.43) | EP300HTR4ALDH1A1SMN1; SMN2KDM1A | |
| SCHEMBL6983529 | 0.78 | HTR4 (0.42) | EP300HTR4ALDH1A1SMN1; SMN2KDM1A | |
| SCHEMBL6987917 | 0.78 | HTR4 (0.42) | EP300HTR4ALDH1A1SMN1; SMN2KDM1A | |
| SCHEMBL6990268 | 0.77 | HTR4 (0.41) | EP300HTR4ALDH1A1SMN1; SMN2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289954-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096303-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |