Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596516 | 0.81 | MTNR1A (0.40) | MTNR1AMTNR1BKEAP1NFE2L2POLB | |
| SCHEMBL6599173 | 0.80 | CA2 (0.42) | MTNR1AMTNR1BKEAP1NFE2L2POLB | |
| SCHEMBL5763500 | 0.79 | MTNR1A (0.51) | MTNR1AMTNR1BKEAP1NFE2L2CMA1 | |
| SCHEMBL6230318 | 0.77 | MTNR1A (0.46) | MTNR1AMTNR1BPOLBHTTNPC1 | |
| SCHEMBL6236325 | 0.76 | MTNR1A (0.43) | MTNR1AMTNR1BPOLBHTTNPC1 | |
| SCHEMBL6130728 | 0.74 | KDM4E (0.54) | MTNR1AMTNR1BPOLBHTTNPC1 | |
| SCHEMBL25030256 | 0.72 | MTNR1A (0.64) | MTNR1AMTNR1BKEAP1NFE2L2ACHE | |
| SCHEMBL25987515 | 0.72 | HTR1D (0.58) | MTNR1AMTNR1B | |
| SCHEMBL6596508 | 0.71 | MTNR1A (0.42) | MTNR1AMTNR1BKEAP1NFE2L2POLB | |
| SCHEMBL3050845 | 0.65 | HTT (0.46) | POLBHTTNPC1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337528-A2 | BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF | LABORATORIOS VITA, S.A. (ES) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002044170-A2 | BENZOTHIOPHENE DERIVATIVE COMPOUNDS, PROCESS OF PREPARATION AND USE THEREOF | LABORATORIOS VITA, S.A. (ES) | 2002-06-06 | — | — | WO | disclosed |