Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | RAB9A | P51151 | 6/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981021 | 0.89 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL8150672 | 0.88 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL13156875 | 0.85 | SMN1; SMN2 (0.73) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL3597627 | 0.84 | SMN1; SMN2 (0.75) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL3594194 | 0.83 | RAB9A (1.00) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL3608132 | 0.81 | SMN1; SMN2 (0.71) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL6799592 | 0.81 | RAB9A (0.77) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL3607419 | 0.78 | LMNA (0.71) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL6981531 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL6968584 | 0.78 | LMNA (1.00) | SMN1; SMN2KDM4EALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934938-B1 | SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-6121301-A | ADMINISTERING TO PREVENT OR TREAT GASTROINTESTINAL DYSMOTILITY; COMPOUNDS SUCH AS 2-((N-(3-CYANOBENZOYL)AMINO)-4-((3-DIISOPROPYLAMINOPROPYL)AMINOCARBONYL)-1,3-THIAZOLE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0934938-A1 | SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |