Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 2/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14243703 | 0.77 | TSHR (0.56) | KMT2AMEN1NPC1RAB9APARP15 | |
| SCHEMBL15682801 | 0.77 | KMT2A (0.55) | KMT2AMEN1APLNRPOLBALDH1A1 | |
| SCHEMBL29576414 | 0.76 | KMT2A (0.53) | KMT2AMEN1APLNRALDH1A1 | |
| SCHEMBL3015241 | 0.76 | KMT2A (0.53) | KMT2AMEN1APLNRALDH1A1 | |
| SCHEMBL31579936 | 0.74 | APLNR (0.67) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL30261137 | 0.74 | ALDH1A1 (0.59) | KMT2AMEN1NPC1RAB9ATSHR | |
| SCHEMBL30831943 | 0.74 | HSD17B10 (0.75) | KMT2AMEN1APLNRPOLBALDH1A1 | |
| SCHEMBL1097902 | 0.74 | HSD17B10 (0.75) | KMT2AMEN1APLNRPOLBALDH1A1 | |
| SCHEMBL29392677 | 0.74 | CYP3A4 (0.62) | KMT2AMEN1APLNRALDH1A1 | |
| SCHEMBL267732 | 0.74 | CYP3A4 (0.62) | KMT2AMEN1APLNRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |