Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1231133 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL1231134 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL1628549 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL16602097 | 0.83 | NPC1 (0.56) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL13645822 | 0.83 | NPC1 (0.56) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL25387995 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL15524362 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL8310016 | 0.83 | NPC1 (0.56) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL14511443 | 0.82 | KMT2A (0.53) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL30140874 | 0.82 | NPC1 (0.55) | ALDH1A1KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071665-B1 | SUBSTITUTED INDOLINONES HAVING AN INHIBITING EFFECT ON KINASES AND CYCLINE/CDK COMPLEXES | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-10-01 | — | — | EP | disclosed |
| US-6169106-B1 | ANTITUMOUR AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-01-02 | — | — | US | disclosed |