Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2143852 | 0.85 | ALDH1A1 (0.62) | LMNAL3MBTL1ALDH1A1POLBALOX12 | |
| SCHEMBL4961749 | 0.83 | PARP1 (0.62) | LMNAL3MBTL1PARP1ALDH1A1POLB | |
| SCHEMBL15346225 | 0.80 | LMNA (0.55) | LMNAL3MBTL1ALDH1A1POLBKDM4E | |
| SCHEMBL12300200 | 0.79 | POLB (0.64) | LMNAL3MBTL1ALDH1A1POLBKDM4E | |
| SCHEMBL23360684 | 0.78 | KMT2A (0.48) | LMNAL3MBTL1ALDH1A1POLBKDM4E | |
| SCHEMBL3447443 | 0.78 | PARP1 (0.55) | LMNAPARP1ALDH1A1ALOX12KDM4E | |
| SCHEMBL4062166 | 0.78 | PARP1 (0.64) | LMNAL3MBTL1PARP1ALDH1A1POLB | |
| SCHEMBL3922378 | 0.78 | PARP1 (0.55) | LMNAL3MBTL1PARP1ALDH1A1POLB | |
| SCHEMBL9001638 | 0.77 | POLB (0.75) | LMNAL3MBTL1POLBKDM4EKMT2A | |
| SCHEMBL16487052 | 0.77 | KMT2A (0.53) | LMNAL3MBTL1ALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |