Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CCR3 | P51677 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986212 | 0.85 | MAPT (0.59) | SMN1; SMN2ALDH1A1PARP1OPRM1OPRD1 | |
| SCHEMBL2143749 | 0.85 | ALDH1A1 (0.57) | GRM4SMN1; SMN2ALDH1A1L3MBTL1HTT | |
| SCHEMBL30073359 | 0.79 | POLB (0.60) | SMN1; SMN2ALDH1A1HTTKDM4EMAPT | |
| SCHEMBL12844486 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HTTKDM4EMAPT | |
| SCHEMBL855339 | 0.79 | POLB (0.60) | SMN1; SMN2ALDH1A1HTTKDM4EMAPT | |
| SCHEMBL4159437 | 0.78 | PARP1 (0.54) | SMN1; SMN2ALDH1A1PARP1HTTHCRTR1 | |
| SCHEMBL19894106 | 0.78 | HCRTR1 (0.60) | HCRTR1HCRTR2CCR3HTR2AHTR2C | |
| SCHEMBL27253846 | 0.78 | KDM4E (0.58) | GRM4SMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL23775498 | 0.78 | HTR2A (0.51) | GRM4ALDH1A1PARP1OPRM1OPRD1 | |
| SCHEMBL16003034 | 0.78 | HTR2A (0.53) | GRM4PARP1HCRTR1HCRTR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |