Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.52 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.49 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.49 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2143724 | 0.85 | ALDH1A1 (0.58) | ALDH1A1HPGDHTTKDM4EHSD17B10 | |
| SCHEMBL6986212 | 0.81 | MAPT (0.59) | PARP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL6984881 | 0.78 | GRM4 (0.54) | PARP1ALDH1A1HTTKDM4EHCRTR1 | |
| SCHEMBL2143763 | 0.77 | PRMT5 (0.58) | ALDH1A1HPGDHTTKDM4EHSD17B10 | |
| SCHEMBL3281765 | 0.76 | MYC (0.49) | PARP1ALDH1A1HPGDHTTKDM4E | |
| SCHEMBL16735636 | 0.75 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL2144202 | 0.75 | HSP90AA1 (0.55) | ALDH1A1HPGDHTTKDM4EHSP90AA1 | |
| SCHEMBL5616088 | 0.74 | HTT (0.59) | ALDH1A1HPGDHTTKDM4EHSD17B10 | |
| SCHEMBL3281405 | 0.74 | HDAC6 (0.50) | ALDH1A1HPGDHTTKDM4EHSD17B10 | |
| SCHEMBL28050846 | 0.73 | PARP1 (0.72) | PARP1ALDH1A1HPGDHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | HSP90AB1, HSP90AA1, HSP90AB2P | PARP1 4089/4885ALDH1A1 678/4885HPGD 1069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.