Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 12/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxymethane SCHEMBL6984939 | 0.83 | P4HB (0.51) | P4HBFBP1PDCD1CD274MAOA | |
| Methoxymethane SCHEMBL6984949 | 0.83 | P4HB (0.51) | P4HBFBP1PDCD1CD274MAOA | |
| SCHEMBL29137842 | 0.82 | APP (0.49) | — | |
| SCHEMBL924068 | 0.81 | FBP1 (0.53) | P4HBFBP1PDCD1CD274GRIN2D | |
| SCHEMBL924069 | 0.81 | FBP1 (0.53) | P4HBFBP1PDCD1CD274GRIN2D | |
| SCHEMBL920739 | 0.79 | FBP1 (0.50) | P4HBFBP1PDCD1CD274GRIN2D | |
| SCHEMBL920740 | 0.79 | FBP1 (0.50) | P4HBFBP1PDCD1CD274GRIN2D | |
| SCHEMBL2774364 | 0.78 | FBP1 (0.65) | P4HBFBP1MAOAMAOBGRIN2D | |
| SCHEMBL1687910 | 0.78 | FBP1 (0.65) | P4HBFBP1MAOAMAOBGRIN2D | |
| SCHEMBL4120811 | 0.78 | FBP1 (0.53) | P4HBFBP1PDCD1CD274MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934265-B1 | AMIDINOPHENYL-PYRROLIDINES, -PYRROLINES, AND -ISOXAZOLIDINES AND DERIVATIVES THEREOF | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6057342-A | INHIBITORS OF TRYPSIN-LIKE SERINE PROTEASE ENZYMES, ESPECIALLY FACTOR XA, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME AS ANTICOAGULANT AGENTS FOR TREATMENT AND PREVENTION OF THROMBOEMBOLIC DISORDERS | DUPONT PHARMACEUTICAL CO. (US) | 2000-05-02 | — | — | US | disclosed |
| EP-0934265-A1 | AMIDINOPHENYL-PYRROLIDINES, -PYRROLINES, AND -ISOXAZOLIDINES AND DERIVATIVES THEREOF | Du Pont Pharmaceuticals Company (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998006694-A1 | AMIDINOPHENYL-PYRROLIDINES, -PYRROLINES, AND -ISOXAZOLIDINES AND DERIVATIVES THEREOF | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |