Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.53 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.45 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.45 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6988005 | 0.99 | PIK3CA (0.52) | PIK3CAPIK3CBPIK3CGIRAK4CLK1 | |
| SCHEMBL27845768 | 0.76 | AR (0.72) | PIK3CAPIK3CBPIK3CGIRAK4DYRK1A | |
| SCHEMBL6985848 | 0.76 | DYRK1A (0.50) | PIK3CAPIK3CGDYRK1ACYP1A2ALDH1A1 | |
| SCHEMBL17801770 | 0.74 | APP (0.57) | PIK3CAIRAK4CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL6984271 | 0.74 | NPC1 (0.52) | DYRK1ACYP1A2ALDH1A1 | |
| SCHEMBL6985095 | 0.73 | CYP11B1 (0.45) | PIK3CADYRK1AALDH1A1 | |
| SCHEMBL6981144 | 0.73 | CYP17A1 (0.50) | DYRK1ASMN1; SMN2TP53 | |
| SCHEMBL6986136 | 0.73 | CYP11B1 (0.48) | DYRK1ACYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL6984570 | 0.73 | MAP3K7 (0.50) | PIK3CADYRK1ACYP1A2ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL6985047 | 0.72 | CYP11B1 (0.44) | PIK3CADYRK1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | DAIICHI PHARMACEUTICAL CO. LTD. | 2003-07-10 | — | — | US | disclosed |
| EP-1283209-A1 | NOVEL BENZOTHIOPHENE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | CYP17A1, CYP21A2, HSD17B1 | PIK3CA 2469/4885PIK3CB 2635/4885PIK3CG 3414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.