Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.46 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985095 | 0.94 | CYP11B1 (0.45) | DYRK1ADYRK1BPIK3CAPIK3CDPIP5K1C | |
| Hydrochloric Acid SCHEMBL6985047 | 0.93 | CYP11B1 (0.44) | DYRK1ADYRK1BPIK3CAPIK3CDPIP5K1C | |
| SCHEMBL6985680 | 0.91 | CYP19A1 (0.50) | DYRK1ADYRK1BPIK3CAPIK3CDPIP5K1C | |
| SCHEMBL6981139 | 0.90 | CYP3A4 (0.54) | DYRK1ADYRK1BPIK3CAPIK3CDCYP3A4 | |
| SCHEMBL6985775 | 0.90 | MAPT (0.55) | DYRK1ADYRK1BPIK3CAPIK3CDPIP5K1C | |
| SCHEMBL6989142 | 0.90 | CYP17A1 (0.50) | DYRK1ADYRK1BPIK3CAPIK3CDPIP5K1C | |
| Hydrochloric Acid SCHEMBL6987641 | 0.89 | CYP17A1 (0.52) | DYRK1ADYRK1BCYP3A4LIMK1ALDH1A1 | |
| SCHEMBL6983734 | 0.89 | CYP2A6 (0.59) | DYRK1ADYRK1BPIK3CAPIK3CDPIP5K1C | |
| SCHEMBL6978941 | 0.89 | AXL (0.59) | DYRK1ADYRK1BPIK3CAPIK3CDPIP5K1C | |
| SCHEMBL6985821 | 0.89 | TDO2 (0.47) | DYRK1ADYRK1BCYP3A4LIMK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | DAIICHI PHARMACEUTICAL CO. LTD. | 2003-07-10 | — | — | US | disclosed |
| EP-1283209-A1 | NOVEL BENZOTHIOPHENE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | CYP17A1, CYP21A2, HSD17B1 | DYRK1A 4799/4885DYRK1B 4688/4885PIK3CA 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.