Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6891346 | 0.87 | ATM (0.66) | KDM4EMAPTATMPOLBCYP19A1 | |
| SCHEMBL680660 | 0.86 | CALM1 (0.71) | CALM1KDM4EGAAMAPTATM | |
| SCHEMBL6986223 | 0.85 | ATM (0.63) | KDM4EMAPTATMPOLBCYP19A1 | |
| SCHEMBL1251843 | 0.83 | KDM4E (0.77) | CALM1KDM4EGAAMAPTATM | |
| SCHEMBL8867447 | 0.83 | CALM1 (0.67) | CALM1KDM4EGAAMAPTATM | |
| SCHEMBL3938308 | 0.83 | CALM1 (0.67) | CALM1KDM4EGAAMAPTATM | |
| SCHEMBL5873476 | 0.83 | CALM1 (0.67) | CALM1KDM4EGAAMAPTATM | |
| SCHEMBL29543507 | 0.83 | KDM4E (0.77) | CALM1KDM4EGAAMAPTATM | |
| SCHEMBL11044914 | 0.83 | CALM1 (0.67) | CALM1KDM4EGAAMAPTATM | |
| SCHEMBL8295694 | 0.83 | CALM1 (0.67) | CALM1KDM4EGAAMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307193-A1 | AGONISTS OF FOLLICLE STIMULATING HORMONE ACTIVITY | Affymax Research Institute (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002009706-A1 | AGONISTS OF FOLLICLE STIMULATING HORMONE ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |