Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6891346 | 0.98 | ATM (0.66) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL11225556 | 0.86 | ATM (0.61) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL6985208 | 0.85 | CALM1 (0.67) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL16641094 | 0.85 | CYP19A1 (0.77) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL31157848 | 0.85 | CYP19A1 (0.77) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL10335393 | 0.83 | CYP19A1 (0.81) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL10343404 | 0.81 | ATM (0.70) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL1486320 | 0.81 | CA2 (0.68) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL30869991 | 0.81 | ATM (0.70) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL31208559 | 0.81 | CA2 (0.68) | ATMKDM4ECA2POLBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307193-A1 | AGONISTS OF FOLLICLE STIMULATING HORMONE ACTIVITY | Affymax Research Institute (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002009706-A1 | AGONISTS OF FOLLICLE STIMULATING HORMONE ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |