Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12098835 | 0.77 | GBA1 (0.46) | TAAR1 | |
| SCHEMBL72389 | 0.77 | GBA1 (0.46) | TAAR1 | |
| SCHEMBL7805384 | 0.74 | HTR3A (0.39) | — | |
| SCHEMBL4161319 | 0.71 | MLNR (0.36) | — | |
| SCHEMBL11821505 | 0.71 | SLC6A4 (0.49) | TAAR1 | |
| SCHEMBL2201795 | 0.70 | SLC6A2 (0.40) | MEN1ALDH1A1KMT2A | |
| SCHEMBL4590823 | 0.69 | HCAR2 (0.31) | — | |
| SCHEMBL4506674 | 0.68 | GBA1 (0.56) | MEN1KDM4AALDH1A1MAPTKMT2A | |
| SCHEMBL1580640 | 0.68 | CYP3A4 (0.44) | ALDH1A1MAPTHSD17B10TAAR1 | |
| SCHEMBL3556706 | 0.67 | HRH4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071680-A4 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | TEXAS BIOTECHNOLOGY CORP (US) | 2003-03-05 | — | — | EP | claimed |
| EP-1071680-A1 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2001-01-31 | — | — | EP | claimed |
| WO-1999052898-A1 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1999-10-21 | — | — | WO | claimed |