Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 7/20 | 0.36 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.36 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 2/20 | 0.35 |
| ▸ | CTSE | P14091 | 2/20 | 0.35 |
| ▸ | PGC | P20142 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4161319 | 0.95 | MLNR (0.36) | HTR3ARENCHIT1CHIA | |
| SCHEMBL4023686 | 0.84 | HTR3A (0.37) | HTR3ASLC6A4 | |
| SCHEMBL72389 | 0.83 | GBA1 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12098835 | 0.83 | GBA1 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11821505 | 0.76 | SLC6A4 (0.49) | HTR3ACYP3A4CYP2D6CYP2C9SLC6A2 | |
| SCHEMBL6985506 | 0.74 | MEN1 (0.36) | — | |
| SCHEMBL1580640 | 0.73 | CYP3A4 (0.44) | CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL595524 | 0.70 | HTR3A (0.50) | HTR3ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4308696 | 0.70 | GBA1 (0.52) | HTR3ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL3441980 | 0.69 | CMA1 (0.35) | RENCYP3A4CYP2D6CYP2C9SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034004-B1 | BENZOPYRANO (2,3-D) TRIAZOLE-DERIVATIVES, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1983-09-28 | — | — | EP | claimed |
| US-6303612-B1 | USED AS ANTIINFLAMMATORY AND/OR ANTIASTHMATIC AGENTS | LECIVA, A.S. (CZ) | 2001-10-16 | — | — | US | disclosed |
| EP-1086079-A1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | Leciva, A.S. (CZ) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999067208-A1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | LECIVA, A.S. (CZ) | 1999-12-29 | — | — | WO | disclosed |