Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697617 | 0.83 | NPC1 (0.42) | TAAR1NPC1RAB9AKMT2ANISCH | |
| SCHEMBL697619 | 0.82 | KMT2A (0.41) | TAAR1NPC1RAB9AF2RL1KMT2A | |
| SCHEMBL697291 | 0.81 | KMT2A (0.46) | TAAR1NPC1RAB9AKMT2ANISCH | |
| SCHEMBL698900 | 0.80 | KMT2A (0.46) | TAAR1NPC1RAB9AF2RL1KMT2A | |
| SCHEMBL1573433 | 0.79 | KMT2A (0.37) | NPC1RAB9AF2RL1KMT2ANISCH | |
| SCHEMBL696517 | 0.77 | TAAR1 (0.47) | TAAR1NPC1RAB9AF2RL1KMT2A | |
| SCHEMBL11137294 | 0.77 | NPC1 (0.42) | NPC1RAB9AKMT2ANISCHALDH1A1 | |
| SCHEMBL705485 | 0.76 | NPC1 (0.38) | NPC1RAB9AF2RL1KMT2ANISCH | |
| SCHEMBL697294 | 0.76 | KMT2A (0.37) | TAAR1NPC1RAB9AF2RL1KMT2A | |
| SCHEMBL1573195 | 0.76 | NPC1 (0.46) | TAAR1NPC1RAB9AKMT2ANISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |