Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | F2RL1 | P55085 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697904 | 0.83 | KMT2A (0.42) | KMT2AF2RL1NPC1RAB9ACES2 | |
| SCHEMBL703857 | 0.80 | KMT2A (0.39) | KMT2AF2RL1NPC1RAB9AMTOR | |
| SCHEMBL705485 | 0.80 | NPC1 (0.38) | KMT2AF2RL1NPC1RAB9ANISCH | |
| SCHEMBL696920 | 0.79 | KMT2A (0.51) | KMT2AF2RL1NPC1RAB9ACES2 | |
| SCHEMBL698561 | 0.79 | TAAR1 (0.44) | KMT2AF2RL1NPC1RAB9AMTOR | |
| SCHEMBL697214 | 0.79 | CES2 (0.41) | KMT2AF2RL1NPC1RAB9ACES2 | |
| SCHEMBL698933 | 0.77 | NPC1 (0.36) | KMT2AF2RL1NPC1RAB9ANISCH | |
| SCHEMBL11137294 | 0.77 | NPC1 (0.42) | KMT2ANPC1RAB9AMTORADK | |
| SCHEMBL27845590 | 0.74 | KMT2A (0.33) | KMT2AF2RL1 | |
| SCHEMBL706123 | 0.74 | NPC1 (0.37) | F2RL1NPC1RAB9ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |