Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | F2RL1 | P55085 | 15/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698933 | 0.86 | NPC1 (0.36) | NPC1RAB9AF2RL1NISCHALDH1A1 | |
| SCHEMBL1573433 | 0.80 | KMT2A (0.37) | NPC1RAB9AF2RL1NISCHALDH1A1 | |
| SCHEMBL703290 | 0.77 | NPC1 (0.44) | NPC1RAB9AF2RL1ALDH1A1 | |
| SCHEMBL698561 | 0.76 | TAAR1 (0.44) | NPC1RAB9AF2RL1NISCHALDH1A1 | |
| SCHEMBL697617 | 0.73 | NPC1 (0.42) | NPC1RAB9ANISCHALDH1A1SMN1; SMN2 | |
| SCHEMBL27845590 | 0.71 | KMT2A (0.33) | F2RL1KMT2A | |
| SCHEMBL697904 | 0.71 | KMT2A (0.42) | NPC1RAB9AF2RL1NISCHSMN1; SMN2 | |
| SCHEMBL11137294 | 0.71 | NPC1 (0.42) | NPC1RAB9ANISCHALDH1A1SMN1; SMN2 | |
| SCHEMBL703857 | 0.71 | KMT2A (0.39) | NPC1RAB9AF2RL1NISCHALDH1A1 | |
| SCHEMBL697814 | 0.70 | RAB9A (0.46) | NPC1RAB9ANISCHALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |