Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985013 | 0.87 | KMT2A (0.39) | KMT2APOLBTDP1ADRA1BADRA1A | |
| SCHEMBL6985492 | 0.86 | POLB (0.38) | KMT2APOLBTDP1ADRA1BADRA1A | |
| SCHEMBL6983790 | 0.83 | KMT2A (0.39) | KMT2APOLBTDP1ADRA1BADRA1A | |
| SCHEMBL4875603 | 0.80 | POLB (0.37) | KMT2APOLBTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL4873840 | 0.80 | POLB (0.37) | KMT2APOLBTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL4876330 | 0.80 | POLB (0.37) | KMT2APOLBTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL6987065 | 0.79 | POLB (0.39) | KMT2APOLBTDP1ADRA1BADRA1A | |
| SCHEMBL4866722 | 0.79 | POLB (0.36) | KMT2APOLBTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL6977033 | 0.78 | KMT2A (0.38) | KMT2APOLBTDP1ADRA1BADRA1A | |
| SCHEMBL6977704 | 0.78 | HTR7 (0.40) | ADRA1BHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289965-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090081-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-29 | — | — | WO | disclosed |