Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | CETP | P11597 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85540 | 0.86 | TSHR (0.63) | TSHRCETPALDH1A1IDO1SRC | |
| SCHEMBL6752075 | 0.83 | TSHR (0.70) | TSHRCETPALDH1A1SRCNPC1 | |
| SCHEMBL12746424 | 0.83 | TSHR (0.59) | TSHRCETPALDH1A1IDO1SRC | |
| SCHEMBL11327519 | 0.82 | TSHR (0.50) | TSHRCETPALDH1A1PDPK1MTOR | |
| SCHEMBL206609 | 0.81 | TSHR (0.68) | TSHRCETPALDH1A1IDO1SRC | |
| SCHEMBL5269070 | 0.81 | TSHR (0.57) | TSHRCETPALDH1A1IDO1SRC | |
| SCHEMBL2415748 | 0.79 | TSHR (0.55) | TSHRCETPALDH1A1IDO1SRC | |
| SCHEMBL11417339 | 0.79 | TSHR (0.55) | TSHRCETPALDH1A1IDO1SRC | |
| Bromide SCHEMBL28778359 | 0.79 | TSHR (0.55) | TSHRCETPALDH1A1IDO1SRC | |
| SCHEMBL3705675 | 0.79 | TSHR (0.65) | TSHRCETPALDH1A1IDO1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459766-A | Fluorosilicone oil containing phosphate and preparation method thereof | 中国科学院上海有机化学研究所 | 2024-08-09 | — | — | CN | claimed |
| CN-110357947-B | Combretastatin A4 derivative | 南京恒远科技开发有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-101220055-B | Method for preparing fluoroquinolone compounds containing phosphoric acid ester group | SHANGHAI YANGFAN MEDICINE TECHNOLOGY LTD | 2011-09-07 | — | — | CN | claimed |
| CN-101100474-B | Fluoroquinolone compound containing phosphate group, preparation method and application thereof in preparing medicine | Shanghai yangfan medicine science and technology co ltd | 2011-06-08 | — | — | CN | claimed |
| US-7704990-B2 | Agents for preventing and treating disorders involving modulation of the RyR receptors | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-04-27 | — | — | US | claimed |
| US-20090292119-A1 | METHODS FOR SYNTHESIZING BENZOTHIAZEPINE COMPOUNDS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-11-26 | — | — | US | claimed |
| CN-101220055-A | Method for preparing fluoroquinolone compounds containing phosphoric acid ester group | SHANGHAI YANGFAN MEDICINE TECH (CN) | 2008-07-16 | — | — | CN | claimed |
| CN-101100474-A | Fluoroquinolone compound containing phosphate group, preparation method and application thereof | SHANGHAI YANGFAN MEDICINE SCIE (CN) | 2008-01-09 | — | — | CN | claimed |
| US-20070049572-A1 | Novel agents for preventing and treating disorders involving modulation of the RyR receptors | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-03-01 | — | — | US | claimed |
| US-20060194767-A1 | Novel agents for preventing and treating disorders involving modulation of the RyR receptors | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2006-08-31 | — | — | US | claimed |
| CN-118459766-A | Fluorosilicone oil containing phosphate and preparation method thereof | 中国科学院上海有机化学研究所 | 2024-08-09 | — | — | CN | disclosed |
| US-11820727-B1 | Capsaicinoid prodrug compounds and their use in treating medical conditions | CENTREXION THERAPEUTICS CORPORATION (US) | 2023-11-21 | — | — | US | disclosed |
| US-11820727-B1 | Capsaicinoid prodrug compounds and their use in treating medical conditions | CENTREXION THERAPEUTICS CORPORATION (US) | 2023-11-21 | — | — | US | disclosed |
| CN-117024658-A | Phospholipid terminal functionalized rare earth isoprene rubber and preparation method and application thereof | 海南天然橡胶产业集团股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-110357947-B | Combretastatin A4 derivative | 南京恒远科技开发有限公司 | 2023-05-26 | — | — | CN | disclosed |
| US-4544667-A | CARBONIC ANHYDRASE INHIBITOR; VISION DEFECTS | MERCK & CO., INC. (US) | 1985-10-01 | — | — | US | disclosed |
| EP-0152340-A1 | 2-Sulfamoylbenzo[b]furan derivatives and ophtalmic composition for the treatment of elevated intraocular pressure | MERCK & CO. INC. (US) | 1985-08-21 | — | — | EP | disclosed |
| EP-0129478-A2 | 2-Sulfamoylbenzo (b) thiophene derivatives, their preparation and pharmaceutical composition for the treatment of elevated intraocular pressure | MERCK & CO. INC. (US) | 1984-12-27 | — | — | EP | disclosed |
| US-4242479-A | CATALYST OF ALUMINUM TRIHALIDE, ORGANOSILOXANE COMPOUND OR ETHER, MAGNESIUM ALCOHOLATE, TITANIUM-HALOGEN AND ORGANOALUMINUM COMPOUNDS | SHOWA YUKA KABUSHIKI KAISHA (JP) | 1980-12-30 | — | — | US | disclosed |
| US-4030933-A | FOR CELLULOSE ACETATES | CELANESE CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049572-A1 | Novel agents for preventing and treating disorders involving modulation of the RyR receptors | RYR2, RYR1, ATP2A1 | TSHR 1830/4885CETP 3752/4885ALDH1A1 1194/4885 |
| US-11820727-B1 | Capsaicinoid prodrug compounds and their use in treating medical conditions | TRPV1, TRPV2, TRPV3 | TSHR 4502/4885CETP 846/4885ALDH1A1 1787/4885 |
| US-20060194767-A1 | Novel agents for preventing and treating disorders involving modulation of the RyR receptors | RYR2, RYR1, ATP2A1 | TSHR 1830/4885CETP 3752/4885ALDH1A1 1194/4885 |
| US-20090292119-A1 | METHODS FOR SYNTHESIZING BENZOTHIAZEPINE COMPOUNDS | KCNB2, KCNJ2, KCNJ5 | TSHR 3363/4885CETP 1211/4885ALDH1A1 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.